
BIOL
141 PHYSIOLOGY (3) Normal functions of the animal body, with special reference
to those of man. Students who have passed Biol. 472 may not schedule this
course
BIOL
142 PHYSIOLOGY LABORATORY (1) Experiments demonstrating basic physiological
principles, with special reference to man. Prerequisite: or concurrent:
BIOL 141
BIOE
201 ANALYSIS OF MOLECULES AND CELLS (3) An analytical study of molecular
and cellular phenomena including functional and metabolic interactions.
Prerequisite: BIOL 141 , CHEM 013 , MATH 141 , PHYS 212
BIOE
301 ANALYSIS OF PHYSIOLOGICAL SYSTEMS (3) Linear systems analysis applied
to electrical networks and lumped parameter models of physiological control
systems. Prerequisite: BIOL 141 , PHYS 212 , MATH 250 or MATH 251
BIOE
302 PHYSIOLOGICAL SIMULATION LABORATORY (1) Computer laboratory designed
to illustrate applications of control systems theory to physiological systems.
Prerequisite: or concurrent: BIOE 301
BIOE
401 INTRODUCTION TO BIOENGINEERING (3) Application of fluid mechanics,
mass transfer, electrical theory, and control theory to physiological systems
and internal artificial organs. Prerequisite: MATH 250 , PHYS 212 . Prerequisite
or concurrent: BIOL 141 or BIOL 472
BIOE
402 BIOMEDICAL INSTRUMENTATION AND MEASUREMENTS (3) Biomedical measurements,
including consideration of techniques, equipment, and safety. Prerequisite:
MATH 250 , 3 CREDITS OF ELECTRICAL CIRCUITS
BIOE
403 BIOMEDICAL INSTRUMENTATION LABORATORY (1) Biomedical measurements laboratory
including measurement of bioptentials, experiments in medical imaging techniques,
and use of cardiovascular and pulmonary system instrumentation. Prerequisite
or concurrent: BIOE 402
BIOE
440 CLINICAL CORELATIONS (1) Engineering analysis applied to common disease
states and therapies. Prerequisite: BIOE 402
BIOE
450W BIOENGINEERING SENIOR DESIGN (3) Application of engineering and physiological
principles to design of artificial organs and life supportive devices.
Prerequisite: BIOE 440 , ENGL 202C , senior standing
BIOE
512 CELL AND MOLECULAR BIOENGINEERING (3) Graduate level cell and molecular
biology course for engineers emphasizing molecular mechanisms.
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Engineering Biomolecules and Medical Devices |
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Bioengineering at Penn State began
with the establishment of an interdisciplinary graduate program
in 1974 as the first of the University’s Intercollege Graduate
Degree Granting Programs. Over the subsequent 25 years, the program
grew to six full time faculty and an associated faculty of about
30 members with primary appointments in the Colleges of Engineering,
Medicine, Science and Health and Human Development. With the impetus
gained from financial support of the Whitaker Foundation, an undergraduate
program was established in 2000. This web portal aims to describe
the design and evolution of this program since its inception, and
the unique features that contribute to its strength and vitality.
The initial design of the undergraduate
program was driven by
the academic interests of its graduate
faculty that resulted in
establishment of a core curriculum with specialization in one of
four areas of concentration: chemical, mechanical and electrical
engineering, and materials science. With the focus of faculty research
split evenly between molecular/cellular bioengineering and medical
devices, the curriculum content of the core and option areas was
motivated by the skills desired of applicants to the graduate program.
It was also expected that one-third of our BS alumni would go on
to graduate school, one-third to medical school and one-third to
industry. To support the premed interests of students, the chemical
engineering option was designed to serve as the premed track since
it contained a greater selection of chemistry courses. As a result,
students with concentration in the chemical engineering track would
only have to take one additional biology course to fulfill our
College of Science’s premed requirements.
With a solid program of engineering sciences in the core and
options, particular attention was paid to providing a thread of
life science coursework throughout the curriculum. Since admission
to the program did not require any prior exposure to biology, it
was assumed that the most efficient way to teach biology was to
employ a reductionist approach. All students were directed to take
first a sophomore biology course on physiology, and its associated
laboratory course, both offered by the department
of biology. These
courses, by design, were intended for allied healthcare professionals
and fulfilled our philosophy that students should be familiarized
with the methods of teaching and learning in the life sciences
that are distinct from the quantitative approach utilized in their
engineering courses. With a solid grounding in physiological systems
at the organ level, students were then exposed to the world of
cell and molecular biology through a course on biomolecular
engineering given by bioengineering faculty. This course is similar a sophomore
course given to biology students, with the addition of a more quantitative
approach to establish the foundations. These courses were followed
up in the junior year with a core course on physiological
systems analysis and its associated computer
laboratory. This sequence
introduced the subject of linear systems analysis and its application
to specific physiological systems through the application of modeling
exercises taught in a hands-on approach using MatLab and similar
programs. In the second semester of the junior year a focused effort
was made to integrate engineering and life science courses with
a course on introduction to bioengineering
design and applications.
This was paralleled by a course on medical
instrumentation and
a hands-on laboratory to teach fundamentals of electronic circuits
and explore specific applications. During the senior year, students
are introduced to clinical applications
of biomedical engineering in a one credit course. This course consists of a sequence of lectures
by physicians who provide an overview of various pathological conditions,
and introduction to clinical practice and specific applications
of medical devices to treat the disease process. This course is
followed in the next semester by a senior
design course that revolves
around the execution of a design project that draws upon the student’s
prior academic experiences.
With this curriculum, undergraduates are well trained in the
engineering sciences and have a solid foundation in the life sciences.
One of the by-products of this approach has been to necessitate
a change in the graduate curriculum. It was found that our undergraduates
were better trained in the biomedical sciences than many of the
applicants to our graduate program who do not come from an undergraduate
program in biomedical/bio engineering. Hence, to expand the life
science base of our graduate students a new
laboratory course in
biomedical sciences was instituted and a new graduate level version
of biomolecular engineering was developed.
Within this framework it is anticipated that both undergraduate and graduate
students will experience a strong life-science oriented approach to teaching
bioengineering while honing their engineering skills. It is anticipated that
the breadth of the undergraduate curriculum will permit it to be viewed as
a true liberal arts program in engineering that prepares students to pursue
future studies in either the life sciences or engineering.
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