DESIGN OF A MOCK CIRCULATORY FLOW LOOP

  TO TEST TISSUE ENGINEERED HEART VALVE PROSTHESES

   BIOENGINEERING SENIOR DESIGN 2007

                 Overview

Approximately 250,000 prosthetic heart valves are implanted each year throughout the world.

Researchers are developing tissue engineered heart valves that they hope will finally provide a solution to problems associated with current implantable valves.

The Penn State Artificial Heart Lab, under the need to adapt equipment, has commissioned our group to design and construct a mock circulatory flow loop for in vitro experimentation and optical analysis of tissue and bioprosthetic heart valves.

Please use the links to the left to explore more information about the process of providing the mock circulatory flow loop shown below.

The mock circulatory flow loop containing the fluid reservoir (A), atrial and aortic compliance chambers (B&C, respectively), resistance module (D), hot plate (E), pulsatile pump (F), and valve test chamber (G).

Funding for this project is courtesy of Dr. Keefe Manning and the Penn State Artificial Heart Lab within the Bioengineering Department.  

Page design by Daniel Bowers

MeChemCo is responsible for the content of this page unless otherwise noted.

Last updated: April 30, 2007