Ryan S. Clement

PhD Bioengineering, 2002
Arizona State University, Tempe, AZ

Assistant Professor of Bioengineering

230 Hallowell Building
University Park, PA 16802-6804

Tel: (814) 865-5190
Fax: (814)863-0490
Email: rclement@psu.edu

 

Research Interests:

My laboratory conducts research related to neural engineering and neuroprostheses. Neural engineering is the application of engineering and technology to repair, augment, or learn about neural systems, while a neuroprosthetic is an electronic device that is designed to restore/augment a specific function through a direct interface with the nervous system. Much of the research effort in our lab is focused on applications of multi-channel neural recordings to improve our understanding of how neurons in the brain interact and process information, and how these neural response patterns are linked to behavior and learning. We are also interested in extracting information from neural signals that might be used in the development of brain-machine interfaces that would allow individuals to control external devices with their brain activity. Tightly linked to these efforts is the desire to improve the neural interface through the novel applications of bioMEMS and other associated technology, as well as signal processing strategies to yield long term reliable performance.

Another area of research in our laboratory is centered on one of the most successful neuroprostheses to date, the cochlear implant. The cochlear implant is a device that is implanted in the inner ear and transforms sound into electrical impulses that stimulate the auditory nerve. While this relatively mature technology has benefited many people with sensorineural hearing loss, there is still high performance variability and much we do not know about the nature of information cochlear implant users are actually receiving. One thrust of our research efforts is to investigate the responses of many neurons simultaneously in the auditory cortex and other centers in the auditory pathway with the use of multichannel neural recording technology. We are particularly interested in stimulation parameter effects and comparing these responses with those from normal acoustic stimulation to gain insight into the fundamental differences between natural and artificial stimulation of the auditory system. In addition to this basic neuroscience research, we are engineering a new technique for objectively fitting cochlear implants based on stapedius muscle electromyogram recordings. It is hoped that this technique will eventually be incorporated into future cochlear implant designs.


Publications:

Clement RS, Visser CT, Rousche P, and Si J. A neuro-integrated robotics platform for brain-machine interface research. IEEE Transactions on Neural Systems and Rehabilitation Engineering. Submitted.

Clement RS, Singh A, Olson B, Lee K, and He J. Neural recordings from a benzocyclobutene (BCB) based intra-cortical neural implant in an acute animal model. Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Cancun, MX. September 2003.

Olson BP, Hu J, Si J, Clement RS, and He J. A support vector approach to online brain control. Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Cancun, MX. September 2003.

Hu J, Si J, Olson BP, Clement RS, and He J. Decoding motor cortical spike trains for brain machine interface applications. Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Cancun, MX. September 2003.

Rousche PJ, Clement R, Visser C, Cruz J, and Si J. Neurabotics: an integration of neurons, tats and robots for advanced studies of brain-computer interface systems. Proceedings of the 1st IEEE Conference on Neural Engineering. Capri, Italy, March 2003.

Clement RS and Kipke DR. Investigations of the electrical stapedius reflex properties using stapedius muscle electromyogram recordings in the rat. Hear Research. In Progress.

Clement RS, Carter PM, and Kipke DR. Measuring the electrical stapedius reflex with stapedius muscle EMG recordings. Annals of Biomedical Engineering, 30(2), pp 169-179. 2002.

Clement RS, Witte RS, Rousche PJ, and Kipke DR. Functional Connectivity in auditory cortex using chronic, multichannel unit recordings. Neurocomputing, 26-27, pp 347-354. 1999.