D.Sc. Electrical Engineering, Washington
University, 1980
Associate Professor of Bioengineering
230 Hallowell Bldg.
Tel:814-865-8092
Fax:814-863-0490
Email:r5g@psu.edu
Dr. Gaumond serves as coordinator of undergraduate programs
in the Bioengineering Department. He teaches courses in Biomedical
Signals and Systems, Physiological Modeling, and Instrumentation.
Research in Dr. Gaumond's laboratory has produced techniques
for the recording and analysis of electrical signals generated
by elements of the nervous system, and is providing new approaches
to the problem of stimulating neural tissue. Equipment development,
animal experiments, tissue culture and analytic modeling techniques
are the focus. Studies of auditory evoked potentials have explored
the use of multi-electrode arrays to specify neural response site
and its progression through the brain stem. Analysis of the statistical
properties of action potential sequences from single fibers in
the auditory system has clarified the role of refractory effects
in structuring information transfer from the auditory periphery
to the brain stem. Applications of neural stimulation using magnetic
induction have led to innovative coil designs to treat obstructive
sleep apnea.
Ongoing work is in two areas. Study of the electrical activity
of groups of cultured neural cells (SK-N-BE2c, P19, and primary
culture hippocampal pyramidal cells) is directed at characterizing
and understanding the electrical signatures associated with synaptogenesis
in vitro. One potential application of this work is the development
of neurosensor systems. Collaborators on these projects include
faculty in the Chemistry and Biology Departments.
A second major area of work involves a collaboration with Ryan
Clement of the Bioengineering Department, seeking to improve the
physical and computational interface between brain and machine
for neuroprosthetic applications.
The Gaumond Laboratory (316 Hallowell Bldg) is equipped with
electronic fabrication, acoustic measurement and calibration equipment,
stereotaxic fixtures for cat and rodent, pipette puller, multi
channel frequency synthesis and spectral analysis equipment. There
is a Meridian ACAS system, including Olympus inverted microscope
and 5-watt Argon laser, and a separate stereo microscope in a Faraday
cage. The lab is housed in a 440 square foot space, with PC-based
data acquisition and processing stations.
Representative Publications
Gaumond, R.P. and S. I. Fried. Analysis of cat multi channel acoustic
brain-stem response data using dipole localization methods. Electroenceph
and Clin Neurophys 63: 376-383, 1986.
Gaumond, R.P. and S. I. Fried. Analysis of cat multi channel acoustic
brain-stem response data using dipole localization methods. Electroenceph
and Clin Neurophys 63: 376-383, 1986.
Gaumond, R.P. Round off errors in signal averaging systems. IEEE
Trans. BME 33: 365-366, 1986.
Gaumond, R.P. and M. Psaltikidou. Models for the generation of
the binaural difference response. J Acoust Soc Am 89: 454-456,
1991.
Gaumond, R.P. Ratio of variance to mean of action potential counts
for an auditory nerve fiber model with 2n-order refractory behavior.
J Acoust Soc Am 93: 2035-2037, 1993.
A. Alkhateeb and R.P. Gaumond Excitation of frog sciatic nerve
using pulsed magnetic fields: effect of waveform variations. proc.
17th Ann. Conf. IEEE/EMBS., IEEE Press, pp. 1-2, 1995.
R.P.Gaumond, J.M. Baker, and S.-H. Jo Magnetic neuromuscular stimulation
for reduction of pharyngeal compliance 9Abstract). Annals of Bioengineering,
Fall meeting, Abstracts, E.28, 1998.
J.P. Stitt, R.P. Gaumond, J.L. Frazier, and F.E. Hanson. Action
potential classifiers: a functional comparison of template matching,
principal components analysis and an artificial neural network,
J. Chemical Senses, 23: 531-540, 1998.
Wolpert, S., W.J. Weiss, and R.P. Gaumond, Editors, Proceedings
of the 24th NE Bioengr Conf. IEEE Press, 1998.
R.P. Gaumond, J.F. Gardner, A.J. Snyder, W.J.Weiss, C.Kelley,
and D. Trumble "Artificial hearts and other organs",
IEEE Encyclopedia oaf Electrical and Electronics Engineering, Vol.1,
pp.656-666, 1999.
R.P. Gaumond, and S.H. Jo. "Breathing Disorder Prescreening
Device and Method," US Patent 6,183,423 B1, 2001.
R.P.Gaumond, R. Silva, J. Moyer A whole-cell neurosensor: Analysis
and simulation of summed asynchronous neural activity. Proc. 28th
Ann. Northeast Bioengineering Conf. IEEE Press (2002)
R.P. Gaumond, R. Silva, J. Zook Summed action potential signal
from a group of neurons. Proc. 25th Ann IEEE/EMBS Conf, IEEE Press
(2003).
R. Silva, R.P. Gaumond, E.W. Barrett, M.V. Phelps, H.R. Allcock,
N. Vasudevan. Neuroblastoma biosensor system, Proc. 30th Northeast
Bioengineering Conf., IEEE Press (2004).
E.W. Barrett, M.V.B. Phelps, H.R. Allcock, R.J. Silva, R.P. Gaumond.
Microcontact printing of poly(organophosphazenes): Potential applications
for selective cell adhesion, Proc. of the Am Chem Society, 228th
meeting, (2004 - awaiting publication).
R.P. Gaumond, R. Clement, R. Silva, D. Sander Estimation of neural
energy in microelectrode signals, J. Neural Engr, (2004 - in review).
|
|
