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Biomedical Engineering

Engineering innovative solutions to modern problems in medicine and biology

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Photo of Siyang Zheng

Siyang Zheng

Assistant Professor

N-238 Millennium Science Complex and 224 Hallowell Building

University Park, PA 16802

Phone: 814-865-8090 / Fax: 814-863-0490

Personal Website:


Ph.D. Electrical Engineering, California Institute of Technology, 2007

Research Interests

My laboratory aims at developing and applying micro/nano technologies for biological and medical applications.  On one hand, I am interested in studying miniaturized devices and systems that can be integrated with biological system in vitro and in vivo.  On the other hand, I am eager to apply these technologies for fundamental biological research, clinic diagnosis and treatment.  The research is highly multidisciplinary, interfacing at engineering, biological sciences, physical sciences, and medicine.  Current focuses are on:

  • Micro/nano fluidic systems to study cancer metastasis
  • Implantable devices for in vivo diagnostics and disease monitoring
  • Lab-on-chip biomarker detection in body fluid
  • Interfacing/interacting biological material with devices

Representative Publications

S. Zheng, J.-Q. Liu, and Y. C. Tai, "Streamline Based Microfluidic Device for Erythrocytes and Leukocytes Separation," IEEE/ASME J. of Microelectromechanical Systems, vol. 17, pp 1029-1038, 2008.

S. Zheng, J. C.-H. Lin, H. L. Kasdan, and Y. C. Tai, "Leukocyte Counting and Differentiation from Undiluted Whole Blood Samples," Sensors and Actuators B Chemical, vol. 132, pp 558-567, 2008.

S. Zheng, M. S. Nandra, C. Y. Shih, W. Li, and Y. C. Tai, "Resonance Induced Impedance Sensing of Human Blood Cells," Sensors & Actuators: A. Physical, vol.145-146, pp 29-36, 2008.

S. Zheng, M. Liu, and Y. C. Tai, "Micro coulter counters with platinum black electroplated electrodes for human blood cell sensing," Biomedical Microdevices, vol. 10, pp 221-231, 2008.

S. Zheng, H. Lin, J.-Q. Liu, M. Balic, R. Datar, R. J. Cote, and Y.-C. Tai, "Membrane microfilter device for selective capture, electrolysis and genomic analysis of human circulating tumor cells," Journal of Chromatography A, vol. 1162, pp. 154-161, 2007.