230 Hallowell Bldg.
Tel:814-865-8092
Fax:814-863-0490
Email:r5g@psu.edu
Dr. Gaumond serves as coordinator of undergraduate programs in the Bioengineering
Department. He teaches courses in Biomedical Signals and Systems, Physiological
Modeling, and Instrumentation.
Research in Dr. Gaumond's laboratory has produced techniques for the recording and analysis of electrical signals generated by elements of the nervous system, and is providing new approaches to the problem of stimulating neural tissue. Equipment development, animal experiments, tissue culture and analytic modeling techniques are the focus. Studies of auditory evoked potentials have explored the use of multi-electrode arrays to specify neural response site and its progression through the brain stem. Analysis of the statistical properties of action potential sequences from single fibers in the auditory system has clarified the role of refractory effects in structuring information transfer from the auditory periphery to the brain stem. Applications of neural stimulation using magnetic induction have led to innovative coil designs to treat obstructive sleep apnea.
Ongoing work is in two areas. Study of the electrical activity of groups of cultured neural cells (SK-N-BE2c, P19, and primary culture hippocampal pyramidal cells) is directed at characterizing and understanding the electrical signatures associated with synaptogenesis in vitro. One potential application of this work is the development of neurosensor systems. Collaborators on these projects include faculty in the Chemistry and Biology Departments.
A second major area of work involves a collaboration with Ryan Clement of the Bioengineering Department, seeking to improve the physical and computational interface between brain and machine for neuroprosthetic applications.
The Gaumond Laboratory (316 Hallowell Bldg) is equipped with electronic fabrication, acoustic measurement and calibration equipment, stereotaxic fixtures for cat and rodent, pipette puller, multi channel frequency synthesis and spectral analysis equipment. There is a Meridian ACAS system, including Olympus inverted microscope and 5-watt Argon laser, and a separate stereo microscope in a Faraday cage. The lab is housed in a 440 square foot space, with PC-based data acquisition and processing stations.
Gaumond, R.P. and S. I. Fried. Analysis of cat multi channel acoustic brain-stem response data using dipole localization methods. Electroenceph and Clin Neurophys 63: 376-383, 1986.
Gaumond, R.P. and S. I. Fried. Analysis of cat multi channel acoustic brain-stem response data using dipole localization methods. Electroenceph and Clin Neurophys 63: 376-383, 1986.
Gaumond, R.P. Round off errors in signal averaging systems. IEEE Trans. BME 33: 365-366, 1986.
Gaumond, R.P. and M. Psaltikidou. Models for the generation of the binaural difference response. J Acoust Soc Am 89: 454-456, 1991.
Gaumond, R.P. Ratio of variance to mean of action potential counts for an auditory nerve fiber model with 2n-order refractory behavior. J Acoust Soc Am 93: 2035-2037, 1993.
A. Alkhateeb and R.P. Gaumond Excitation of frog sciatic nerve using pulsed magnetic fields: effect of waveform variations. proc. 17th Ann. Conf. IEEE/EMBS., IEEE Press, pp. 1-2, 1995.
R.P.Gaumond, J.M. Baker, and S.-H. Jo Magnetic neuromuscular stimulation for reduction of pharyngeal compliance 9Abstract). Annals of Bioengineering, Fall meeting, Abstracts, E.28, 1998.
J.P. Stitt, R.P. Gaumond, J.L. Frazier, and F.E. Hanson. Action potential classifiers: a functional comparison of template matching, principal components analysis and an artificial neural network, J. Chemical Senses, 23: 531-540, 1998.
Wolpert, S., W.J. Weiss, and R.P. Gaumond, Editors, Proceedings of the 24th NE Bioengr Conf. IEEE Press, 1998.
R.P. Gaumond, J.F. Gardner, A.J. Snyder, W.J.Weiss, C.Kelley, and D. Trumble "Artificial hearts and other organs", IEEE Encyclopedia oaf Electrical and Electronics Engineering, Vol.1, pp.656-666, 1999.
R.P. Gaumond, and S.H. Jo. "Breathing Disorder Prescreening Device and Method," US Patent 6,183,423 B1, 2001.
R.P.Gaumond, R. Silva, J. Moyer A whole-cell neurosensor: Analysis and simulation of summed asynchronous neural activity. Proc. 28th Ann. Northeast Bioengineering Conf. IEEE Press (2002)
R.P. Gaumond, R. Silva, J. Zook Summed action potential signal from a group of neurons. Proc. 25th Ann IEEE/EMBS Conf, IEEE Press (2003).
R. Silva, R.P. Gaumond, E.W. Barrett, M.V. Phelps, H.R. Allcock, N. Vasudevan. Neuroblastoma biosensor system, Proc. 30th Northeast Bioengineering Conf., IEEE Press (2004).
E.W. Barrett, M.V.B. Phelps, H.R. Allcock, R.J. Silva, R.P. Gaumond. Microcontact printing of poly(organophosphazenes): Potential applications for selective cell adhesion, Proc. of the Am Chem Society, 228th meeting, (2004 - awaiting publication).
R.P. Gaumond, R. Clement, R. Silva, D. Sander Estimation of neural energy in microelectrode signals, J. Neural Engr, (2004 - in review).