231 Hallowell Bldg.
University Park, PA 16802
Tel: 814-865-1407
Fax: 814-863-0490
Email:kksbio@engr.psu.edu
Lab Page:http://www.bioe.psu.edu/NIH_transducer.html
Ultrasonic scattering in biological tissues
Research in the area of ultrasonic characterization of biological tissues, especially blood, has been supported by an NIH grant (HL28452) for more than 16 years. The objective of the grant is aimed at elucidating the fundamental mechanisms involved in the echogenicity of tissues in an ultrasonic image. More than 10 Ph.D. theses and 12 M.S. theses have resulted from this work. One postdoc from Canada and one visiting faculty member from Taiwan have participated in this research. Three Ph.D. students are currently working in the area.
Ultrasonic contrast agents
Ultrasonic characterization of ultrasonic contrast agents and the applications of contrast agents for flow measurements and imaging has been pursued. The work has been supported by an NIH grant and an industrial grant. Two M.S. theses and two Ph.D. theses have resulted from this work.
Ultrasonic transducer engineering
Research in medical ultrasonic transducer engineering has been supported initially by a Whitaker Special Opportunity Award and now by an NIH National Resource grant (RR1 1795) on transducer technology. The thrust is on very high frequency ultrasonic transducers and arrays which are and can be used for dermatological, ophthalmological and intravascular imaging. This is the only NIH technology resource in medical ultrasound in the country. Collaboration is being pursued with 7 universities and one company. It is supporting one full time engineer, two technicians, 3 postdocs, and 5 graduate students. Two M.S. theses and one Ph.D. thesis have so far resulted from this work.
S.J. Wu and K.K. Shung. An in vitro study of the effects of Doppler angle, fibrinogen and hematocrit on ultrasonic Doppler power from blood. IEEE Trans. Ultrasonics, Ferroelectrics, and Frequency Control 46. 197-204, 1999.
S.J. Wu, K.K. Shung and J.G. Brasseur. In situ measurement of Doppler power vs. Flow turbulence intensity in red cell suspensions. Ultrasound in Medicine and Biology 24: 1009-1021, 1998.
M.J. Zipparo, K.K. Shung and T. Shrout. Piezoceramics for high frequency (50-100 MHz) single element imaging transducers. IEEE Trans. Ultrasonics, Ferroelectrics, and Frequency Control 44: 1038-1048, 1997.
K.K. Shung and M. Zipparo. Ultrasonic transducers/arrays. IEEE Engineering in Medicine and Biology Magazine 15: 30, 1996.
P.H. Chang, K.K. Shung and H. Levene. Quantitative measurements of second harmonic Doppler using ultrasound contrast agents. Ultrasound in Medicine and Biology 22: 1205-1214, 1996.