Surface based control of cellular functions can have a significant impact on biomaterial-based regenerative therapies. Because of this, it is crucial to investigate the mechanobiological control mechanisms governing substrate initiated cell signaling in order to better design polymer constructs and drug delivery strategies.
In the Musculoskeletal Regenerative Engineering Lab, we are focused on understanding the fundamental mechanisms by which biomaterial interfaces alter the proliferation, migration, and differentiation of mesenchymal stem cells to guide rational biomaterial design and facilitate the generation or regeneration of musculoskeletal tissues.
Acknowledgement of Land
As a lab at The Pennsylvania State University, we would like to acknowledge that we conduct our research on the original homelands of indigenous peoples who were the first stewards and scientists of Pennsylvania. Please see our lab culture page to learn more.