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Principal Investigator
Research Interests:
Biomechanics. Cellular engineering and
cell mechanics. Cellular behavior and mechanism in response to physical
and chemical stimulation, with focuses on the inflammatory process, cancer
immunoeditting and metastasis. Engineering applications to
cell and molecular biology, including cell deformation, cell-cell
adhesion, cell signaling, cell migration and motility.
Professional Affiliations:
Fellow, American Institute for Medical and
Biological Engineering (AIMBE).
Fellow, The Biomedical Engineering Society (BMES).
Board of Director (1999-2002), BMES.
Member, The United States National Committee on Biomechanics (USNCB).
Member, The American Society of Mechanical Engineers (ASME).
Member, The North American Society of Biorheology (NASB).
Secretary
(1998-present), NASB.
Associate Editor, ASME - Journal of Biomechanical Engineering.
Managing Editor, Frontiers in Bioscience.
Current Group Members
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Payal Khanna - I
graduated from Virginia Commonwealth University in 2006 with my
Master’s degree in Biomedical Engineering. Before joining Dr. Dong’s
group, my research focused on the synergistic interactions between the
ChK 1 inhibitor, UCN-01, and farnesyltransferase inhibitors (mainly
statins) in leukemia. I chose to pursue my PhD degree in Dr. Dong’s
lab since my interests lie in cancer-related research. Currently, my
work focuses on elucidating the roles of cell signaling pathways in
tumor metastasis and transendothelial migration.
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Shile (Shel) Liang -I graduated from Tianjin University,
P.R. China, in 2002 with a Master Degree in Biochemical Engineering.
Before I arrived at Penn State, my research work is related to Taxol®,
which is an active anticancer drug. Therefore, I chose Dr. Dong's lab to
pursue my Ph.D. degree so that I can develop my interests in
cancer-related research. I am a Penn State Huck Institute for Life Sciences
Fellow, too. |
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Meghan (Henty) Hoskins - I received my BS in
2001 and MS in 2003, both in Mechanical
Engineering from Penn State. My Master's research was conducted with
Dr.
El-Gindy at the Pennsylvania Transportation Institute on the finite
element
simulation of a pickup truck rollover. In the Fall of 2003, I began
my pursuit
of a PhD in Bioengineering here at Penn State in Dr. Dong's Lab. I
am working
on the Mechanisms of Melanoma Tumor Cell Extravasation project in which I
will
focus on the fluid mechanics involved in tumor cell capture by endothelial
and
white blood cells.
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Chong Haw Kwang -
I graduated from the National
University of Singapore in 2004 with a bachelor's degree in Chemical
Engineering. During my undergraduate years I felt that my interests
drawn to the area of biology and engineering. Hence, with chemical
engineering training as my background, I believe I can contribute
greatly to this field. In Dr Dong's lab, my current research focuses
on possible mechanisms of adhesion and capture of tumor cells from the
bloodstream and particular proteins that aid metastasis of these cells
across the endothelial. |
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UNDERGRADUATE STUDENTS
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Maria Rozploch |
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Patricia Groleau - I am a Senior undergraduate in
the Department of Biology with intentions of attending medical
school after graduation. My current research involves validating the
mouse as a model for human melanoma extravasation both in vivo
and in vitro. This past summer I participated in the
Biomaterials and
Bionanotechnology summer program (BBSI) with Dr.
Dong where I began testing melanoma migration in vivo |
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Tara Yukinis - I am an undergraduate Bioengineering
major (Chemical Engineering option) who has been working in Dr. Dong's lab
since September 2006. I first began working with then current PhD student
Hsin-Hsin Peng, continuing work on her thesis dealing with quantitative
analysis tools for mapping cellular interactions. I am currently working
on a collaboration with grad student, Payal Khanna |
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Photos from previous years
Ph.D. Alumni
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Cao, Jian |
Senior Biomedical Engineer
Medtronic, Inc.
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Ph.D. 1997 |
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You, Jun |
Assistant Professor
Hershey Medical Center- PSU
Musculoskeletal Research Lab
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Ph.D. 1997 |
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Lei, Xiao-Xiao |
Campus Minister
University of Pittsburgh
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Ph.D. 1999 |
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Hodgson, Louis |
Research Associate Professor
University of North Carolina
Pharmacology |
Ph.D. 2002 |
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Maggie
Slattery |
Assistant Professor
Pennsylvania State University
Bio Engineering |
Ph.D. 2006 |
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Hsin-Hsin Peng |
Postdoctoral Fellow
National
Cheng-Kung University
Taiwan |
Ph.D. 2007 |
M.S. Alumni
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Perkowski,
Karen |
Merck and
Co. Inc
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M.S. 1998 |
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Rank, Brad |
Wyeth
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M.S. 1999 |
Undergraduate Alumni
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Barnes, Ashley (1998) |
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Barraco, Jennifer (1999) |
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Fire, Joe ( 2000) |
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Gross, Chris (1996) |
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Hann, Matthew (1999) |
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Houser, Anthony |
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Leyton-Mange, Jordan (2005) |
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Scarbourgh, Gary (1996) |
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Shung, Simon (1997) |
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Sourwine, Maraileen (1997) |
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Desi Wagner (2006) |
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