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Schedule of Classes

Bioengineering Undergraduate and Graduate Courses

100S Bioengineering Seminar (1) First-year seminar to introduce the role of engineering in biomedical research and in instrument development for the medical device industry. Professor Margaret Slattery.

201 Analysis of Molecules and Cells (3) An analytical study of molecular and cellular phenomena including functional and metabolic interactions. Prerequisite: BIOL 141 , CHEM 112 , MATH 141 , concurrent PHYS 212. Professor Will Hancock.

301 Analysis of Physiological Systems (3) Linear systems analysis applied to electrical networks and lumped parameter models of physiological control systems. Prerequisite: BIOL 141 , PHYS 212 , MATH 250 or MATH 251, concurrent BIOE 302. Professor Ryan Clement.

302 Physiological Simulation Laboratory (1) Computer laboratory designed to illustrate applications of control systems theory to physiological systems. Prerequisite: or concurrent: BIOE 301. Professor Ryan Clement.

303 Bio-continuum Mechanics (3) Mechanical properties of fluids and solids with applications to tissue mechanics and vascular system. Prerequisite: BIOL 141 , E MCH 210 , MATH 230, MATH 251. Professor Cheng Dong.

313 Biothermodynamics (3) Chemical processes, including material and energy balances and phase equilibria, with emphasis on biological applications. Prerequisites: BIOL 141 , CHEM 112, MATH 230 , MATH 251. Professor Margaret Slattery.

401 Introduction to Bioengineering (3) Challenges and constraints of bioengineering research and design. Emphasis on immunoresponse, tissue mechanics, biological transport phenomena, and biomaterials. Prerequisite: BIOE 201 , BIOE 303, Concurrent: BIOE 404. Professor Peter Butler.

402 Biomedical Instrumentation and Measurements (3) Biomedical measurements laboratory including measurement of bioptentials, experiments in medical imaging techniques, and use of cardiovascular and pulmonary system instrumentation. Prerequisite or concurrent: MATH 250 or MATH 251, BIOE 301 or EE210 or EE 305 or PHYS 402. Professor Nadine Smith.

403 Biomedical Instrumentation Laboratory (1) Biomedical measurements laboratory, including measurement of biopotentials, experiments in medical imaging techniques, and use of cardiovascular and pulmonary system instrumentation. Prerequisite: BIOE 402. Professor Nadine Smith.

404 Data Analysis and Experiment Design (1) Statistical measures of data, and selection of experiment sample size to meet criteria. Prerequisite: BIOE 302 Concurrent: BIOE 401. Professor Andrew Webb.

406 Medical Imaging (3) Physical principles and clinical applications of medical imaging methods. Prerequisite: PHYS 212. Professor Andrew Webb.

409 Biofluid Mechanics (3) The fundamental relations in fluid mechanics and their application to biofluids including steady/unsteady flows, diseased states, devices and biorheology. Prerequisites: MATH 230 , MATH 251 , BIOE 303. Professor Keefe Manning.

413 Bioengineering Transport Phenomena (3) An integrated study of the fundamentals of mass transport processes with emphasis on the analysis of physiological systems. Prerequisite: BIOE 303 , BIOE 313 or CHEM 450. Professor Margaret Slattery.

419 Artificial Organs and Prosthetic Devices (3) Analysis of function and consideration of design concerns for biomedical implants, including prosthetic joints, electrical stimulators, and cardiovascular pumps. Prerequisite: MATH 250 . Prerequisite or concurrent: BIOL 141 or BIOL 472. Professor Keefe Manning.

423 Reaction Kinetics of Biological Systems (3) Chemical kinetics and reaction equilibria with applications to the analysis of physiological function and the design of synthetic organs. Prerequisite: BIOL 141 , BIOE 313 or CH E 210 . Prerequisite or concurrent: BIOE 413 or CH E 302 and CH E 413. Professor Ahmed Heikal.

440 Clinical Correlations (1) Engineering analysis applied to common disease states and therapies. Prerequisite: BIOE 402. Professor Peter Butler.

443 Biomedical Materials (3) Describe properties of materials and composites and their in vivo interactions.

444 Surfaces and the Biological Response to Materials (3) Focus is on the special properties of surfaces as an important causative and mediating agent in the biological response to materials.

450W Bioengineering Senior Design (3) Application of engineering and physiological principles to design of artificial organs and life supportive devices. Prerequisite: BIOE 440 , ENGL 202C , senior standing. Professor Nadine Smith.

490 Colloquium (1) Technical presentations related to research and industry concerns, and by students doing senior projects. Prerequisite: or concurrent: BIOE 450W.

496 Independent Studies (1-18) Opportunity for advanced undergraduate students to study indepenently in consultation with a faculty advisor.

497 Special Topics (1-9) This designation is assigned to new or developing undergraduate courses covering specialized areas of interest in bioengineering and course offerings may be infrequent. Past offerings have focused on topics such as artifical organs, medical ultrasound imaging and biomedical instrumentation.

497E Magnetic Resonance Systems (3) Fundamentals of hardware and applications of nuclear magnetic resonance, magnetic resonance imaging, and nuclear quadrupolar resonance. Prerequisites: EE 330, EE 350, BIOE 301 or PHYS 400.

501 Bioengineering Transport Phenomena (3) Application of the equations of mass, energy, and momentum conservation to physiological phenomena and to the design of artificial organs.

502 Introduction to Bioelectric Phenomena (3) Electric phenomena in nerve and muscle membrane potentials, Hodgkin-Huxley equations, volume conductor problem, applications to electrocardiography, electroencephalography, plethysmography. Professors David Geselowitz.

503 Fluid Mechanics of Bioengineering Systems (3) Cardiovascular system and blood flow, non-Newtonian fluid description, vessel flows, unsteady flows and wave motion, windkessel theory, transmission line theory. Professor Keefe Manning.

504 Physiological Systems Analysis (3) Application of systems theory, control theory, and analytic modeling strategies to the study of physiological systems. Prerequisites: BIOL 472, MATH 250.

505 Bioengineering Mechanics (3) Application of the principles of continuum mechanics to characterization of the passive and active mechanical properties of soft and hard tissues and their constituent cells. Fundamentals of the description of stress and strain and advanced topics in viscoelasticity are considered to describe the normal and diseased state at the tissue, cellular and molecular level. Prequisites: EMCH 210, ME033 or equivalent. Professor Cheng Dong.

506 Medical Imaging (3) Medical diagnostic imaging techniques, including generation and detection of ultrasound, X-ray, and nuclear radiation; instrumentation and biological effects. Prerequisite: PHYS 202. Professor Nadine Smith.

507 Biomedical Signal Processing (3) Data acquisition and digital signal processing focusing on bimedical signal processing issues, including linear phase filters, spectral analysis and wavelets.Prerequisites: BIOE 401, 402, Bioll 041 or 472, Math 250. Professor Nadine Smith.

508 (MATSE 508) Biomedical Materials (3) Properties and methods of producing metallic, ceramic, and polymeric materials used for biomedical applications. Professor Paul Brown.

510 Biomedical Applications of Microelectromechanical Sytems (BIOMEMS) and Bio Nanotechnology (3) Effective Date: SP2005 Introduction to BioMEMS and Bionanotechnology. Topics include: electromechanical and chemical biosensors, microfluidics microscale separations, and surface patterning for cellular engineering. Prerequisite: E E 418, BIOE 201.

512 Cell and Molecular Bioengineering (3) Graduate level cell and molecular biology course for engineers emphasizing molecular mechanisms. Professor William Hancock.

515 Cellular Mechanics and Biophysics (3). Advanced topics and recent developments in cellular engineering; applications of engineering science to cell biology. Prerequisite: BIOE 505. Professor Cheng Dong.

516 Ultrasonic Imaging (3) Advanced topics and recent developments in ultrasonic imaging will be discussed. Prerequisite: BIOE506 or equivalent.

517 (MATSE 517) Biomedical Materials Surface Science (3) Special properties of surfaces as an important causative and mediating agent in the biological response to materials. Professor Erwin Vogler.

519 Artificial Organ Design (3) Basic techniques and principles of a multidiscipline approach to artificial organs design. Prerequisites: None. Professor Keefe Manning.

536 Ultrasonic Tranducer Arrays (3) Theory, design, fabrication and testing of ultrasonic transducer arrays. Prerequisite: BIOE 506 or BIOE 516.

552 (EMCH 552, IE 552)Mechanics of the musculoskeletal System (3) Structure and Biomechanics of bone, cartilage, and skeletal muscle; dynamics and control of musculoskeletal system models. Prerequisite: consent of program. Prerequisite or concurrent: BIOL 472. Professor Pytel and Professor Andris Freivalds.

553 (IE 553) Engineering of Human Work (3) Physics and physiology of humans at work; models of muscle strength; dynamic movements; neural control; physical work capacity; rest allocation. Prerequisite: BIOL 041 or 472. Professor Andris Freivalds.

576 Bioengineering of the Cardiovascular System (3) Experimental and analytical studies of network branching patterns, regional blood flow, rheology and mechanics of blood cells and vessels as they affect physiological function. Prerequisite: BIOL 472. Professor Herbert Lipowsky.

580 Bioengineering Internship (3) Supervised experience at the Milton S. Hershey Medical Center, including rotation through services and work on a minor project. Prerequisite: BIOE 402, 3 credits in Bioengineering at the 500 level. Professor Snyder.

590 Bioengineering Colloquium (1) Weekly series of seminars by speakers from outside and within Penn State University on new and developing research areas in bioengineering, and presentations by registered students on their thesis research. All students are required to attend; M.S. degree students must register at least once and Ph.D. students must register at least twice during their thesis research.

596 Individual Studies (1-9) Opportunity for advanced graduate students to study independently in consultation with a faculty advisor.

597 Special Topics (1-9) This designation is assigned to new or developing graduate courses covering specialized areas of interest in bioengineering. Past offerings have focused on topics such as advanced studies of cardiovascular function, advanced topics in artificial organ design and cellular biomechanics.