Welcome to the Transformative Biomaterials and Biotechnology Lab (TBBL) at The Penn State University. Our research interests are to investigate a methodology for functional biomaterial development and use biomaterials as a tool to solve unmet clinical problems.

Currently, our research projects include: 1) Methodology for new biomaterial development; 2) soft and hard tissue engineering; 3) cancer drug delivery and imaging; 4) stem cell/biomaterial interactions; 5) micro-/nano-medical device fabrication; 6) biosensing.



News reports on our biodegradable optical fiber work in "Biomaterials". PSU news; BIG 10 news; Medgadget.com.


Congratulation to Gloria Kim who has successfully defended her PhD dissertation.


Congratulation to the following students.

Graduate students, Dingying Shan, Chuying Ma both received CAB-BM Young Investigator Merit Award at the 254th American Chemical Society (ACS) National Meeting held in Washing DC. They both presented at the ACS Symposium of Biomaterials Science and Translational Medicine.

Graduate student, Qiyao Li recieved Best Poster Award at the 254th American Chemical Society National Meeting. (only 3 poster awards out of nearly 200 posters)

Summer REU student, Kelly Miller won the first place in the poster competition out of 65 posters of the PSU Multi-Campus REU program.


Congratulation to Jimin Kim to receive Leighton Riess Graduate Fellowship in Engineering.


Yang laboratory has published 100 papers (92 journal articles and 8 book chapters) as of 3/3/2017. Many thanks to all our collaborators, current and past students and postdocs.


Congratulations to Julianne Baker and Hui Xu on their new co-op jobs!

Julianne Baker, a junior in biomedical engineering with a minor in engineering leadership development and Hui Xu, a senior in biomedical engineering, will be participating in co-ops at Bristol-Myers Squibb and Johnson & Johnson, starting in January 2017. Julianne joined the lab in May 2016 and Hui joined the lab in January 2016. Both will be able to apply their technical skills and conceptual knowledge to real industry situations. Congratulations again!

Also, congratulations to undergraduate students, Ye Zhu and William Tz-Je Su on receiving PSU College of Engineering Research Initiative (CERI) awards to work in TBBL in Spring 2017.


In collaboration with Prof. Cheng Dong, the immune-cell mediated cancer drug delivery work was accepted by Small. PSU News, NSF weekly banner and highlight


Congratulation to Jimin Kim whose sweat chloride sensing paper was just accepted by "Chemical Science". News: PSU News; Science Daily, Phys.org, Futurity (Image of the day). NIBIB news.


TBBL is proud of supporting all our undergraduate student researchers.

Congratulations to Demetrius Harris for winning "2016 Undergraduate Exhibition Award" the third place in Engineering.

Congratulations to John Fadel for having been selected for PPG Undergraduate Research Fellowship for Summer 2016.

Congratulations to Samantha Kirk for having been selected for the summer 2016 Erickson Discovery Grant.

Congratulations to Brady Goulden for his $1000 award from Office of Science Engagement at PSU.


Scaffold degradation modeling work was featured on IE Magzine. Congratulation to collaborators Dr. Li Zeng at Texas A&M and Dr. Xinwei Deng at Virginia Tech.


Congratulation to Jinshan and all co-authors, the work on antibacterial and antifungal bioglue was accepted by Biomaterials.


Dr. Jian Yang was elected to the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows Class of 2016. Congratulations. News release (01/25/16)


Adv Mater 2014 (click polymer)
Adv Mater 2014 (BPLP-PLA)

PNAS 2009 (BPLP)
ACS Nano 2014 (In situ endothelium repair)

Chemical Science 2017 (Fluorescent sensor for cystic fibrosis diagnosis)

Small 2017 (Immune cell-mediated drug delivery)

Acta Biomaterialia 2017 (Complete story of citrate fluorescence mechanism)

Positions Available

Postdoctoal fellow position (Please send your CV to Dr Jian Yang via email: jxy30@psu.edu to inquire the availability of positions.

PhD candidates: We are always seeking highly self-motivated and intelligent PhD students to work on biomaterials, stem cells, and tissue engineering projects. Students who have a strong background in any of the following disciplines: bioengineering, chemical engineering, material science engineering, chemistry, biology are all welcome to apply.

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